What headache meds can you take while pregnant

It can be tough to navigate all the aches and pains of pregnancy while also keeping your growing baby safe. Here's what to know when your head is throbbing and you're desperately searching for relief.

What could be causing your headache

“It’s absolutely essential to figure out the cause of the headache before attempting to treat it,” said Dr. James Bernasko, Director of the Regional Perinatal Center at Stony Brook Children's Hospital. Pregnancy headaches can range from "the merely inconvenient to the actually life-threatening,” so context is particularly important, Bernasko added.

Possible causes include:

  • Fatigue
  • Stress
  • Eye strain
  • Dehydration
  • Nasal congestion
  • Hormonal fluctuations
  • Caffeine withdrawal
  • Migraine
  • Preeclampsia

If you have a family history of high blood pressure, stroke, or aneurysms, or you are experiencing the "worst headache of your life," call your provider immediately, Bernasko said.

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What headache meds can you take while pregnant
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What could help your headache

Non-pharmacological options

"Sometimes, something as simple as chocolate can trigger a headache" during pregnancy, so it's worth testing out a few non-pharmacological remedies first, Bernasko said. If you're suffering from chronic headaches, consider acupuncture or biofeedback, a technique that allows you to channel and dissipate your pain.

Things to try:

  • Warm compress on the face (sinus headache)
  • Cold compress on the back of the neck (stress headache)
  • Meditation
  • Massage

Over-the-counter medication options

Tylenol

Tylenol, sold as the generic acetaminophen, is "the safest headache medication" during pregnancy and is not associated with any known birth defects, according to Bernasko. However, you should avoid taking more than 1500 milligrams within 24 hours as overuse can damage your liver.

Ibruprofen, aspirin, naproxen (NSAID)

This group of pain relievers is known as NSAIDs (non-steroidal anti-inflammatory drugs). They should only be taken after consulting with your doctor, as prolonged use can irritate the stomach and affect blood flow in the baby’s heart, Bernasko said.

However, “if Tylenol hasn’t worked for you in the past... you can take one pill of any of [the above] and then reach out to your provider," Bernasko said. The bottom line: NSAIDs are "not something you should take multiple times without your provider knowing.”

Caffeine

"During some types of headaches your blood vessels enlarge... Caffeine can help stop this action" because it constricts your blood vessels, wrote Dr. Talia Gates, an OB/GYN in Jasper, Alabama, in an email to TODAY. Gates recommends combining Tylenol and a caffeinated drink for dual relief.

Yet as Bernasko points out, caffeine withdrawal or overdose could have caused your headache in the first place, so make sure to factor in how much you've already consumed.

Prescription options

Narcotics, also known as opioids, are "everywhere now," Bernasko said, so it can be tempting to pop one for a headache. However, these medications can be addictive and "should only be taken under direct medical supervision," Bernasko explained. Additionally, prolonged use of narcotics can cause your baby to develop neonatal abstinence syndrome and undergo a painful withdrawal process after birth.

Narcotic analgesic combinations, which contain acetaminophen or an NSAID in addition to an opioid, pose similar risks. Yet if your over-the-counter options are falling short, your doctor may suggest one of the "safe medications" within this group, said Gates.

Triptans (migraine medication)

If you've already been prescribed a triptan for migraines, it's safe to continue using during pregnancy, Bernasko said. Otherwise, consult your doctor to find the right medication for your symptoms.

What headache meds can you take while pregnant

For years, products containing acetaminophen, such as the pain reliever Tylenol, were largely viewed as safe to take during pregnancy. Hundreds of widely available over-the-counter remedies, including popular cold, cough, and flu products, contain acetaminophen. Not surprisingly, some 65% of women in the US report taking it during pregnancy to relieve a headache or to ease an aching back.

But recently, a group of doctors and scientists issued a consensus statement in Nature Reviews Endocrinology urging increased caution around acetaminophen use in pregnancy. They noted growing evidence of its potential to interfere with fetal development, possibly leaving lingering effects on the brain, reproductive and urinary systems, and genital development. And while the issue they raise is important, it’s worth noting that the concerns come from studies done in animals and human observational studies. These types of studies cannot prove that acetaminophen is the actual cause of any of these problems.

An endocrine disruptor

Acetaminophen is known to be an endocrine disruptor. That means it can interfere with chemicals and hormones involved in healthy growth, possibly throwing it off track.

According to the consensus statement, some research suggests that exposure to acetaminophen during pregnancy — particularly high doses or frequent use — potentially increases risk for early puberty in girls, or male fertility problems such as low sperm count. It is also associated with other issues such as undescended testicles, or a birth defect called hypospadias where the opening in the tip of the penis is not in the right place. It might play a role in attention deficit disorder and negatively affect IQ.

Risks for ill effects are low

If you took acetaminophen during a current or past pregnancy, this might sound pretty scary — especially since you’ve probably always considered this medicine harmless. But while experts agree it’s important to consider potential risks when taking any over-the-counter or prescription medicines during pregnancy, you shouldn’t panic.

"The risk for an individual is low," says Dr. Kathryn M. Rexrode, chief of the Division of Women's Health, Department of Medicine at Harvard-affiliated Brigham and Women's Hospital.

Chances are pretty good that if you took acetaminophen during a pregnancy, your baby likely did not, or will not, suffer any ill effects.

The research on this topic is not conclusive. Some information used to inform the consensus statement was gathered from studies on animals, or human studies with significant limitations. More research is needed to confirm that this medicine is truly causing health problems, and to determine at what doses, and at what points during a pregnancy, exposure to acetaminophen might be most harmful.

Sensible steps if you’re pregnant

Three common-sense steps can help protect you and your baby until more is known on this topic:

  • Avoid acetaminophen during pregnancy when possible. Previously during preconception and pregnancy counseling, Dr. Rexrode had warned patients against using NSAID drugs, such as Advil and Aleve, and suggested taking acetaminophen instead. "Now I also tell people that some concerns have been raised about acetaminophen use during pregnancy, and explain that its use should be limited to situations where it is really needed," says Dr. Rexrode. In short, always consider whether you really need it before you swallow a pill.
  • Consult with your doctor. Always clear acetaminophen use with your doctor, particularly if you are going to be using the medicine for a long period of time. They might agree that taking it is the best option — or suggest a safer alternative.
  • Minimize use. If you do need to take acetaminophen during pregnancy, take it for the shortest amount of time possible and at the lowest effective dose to reduce fetal exposure. "This advice about the lowest necessary dose for the shortest period of time is generally good counseling for all over-the-counter medication use, especially during pregnancy," says Dr. Rexrode.

While all of this is good advice for using acetaminophen, there are times when it’s riskier not to take it. For example, if you have a high fever during pregnancy — which can harm your baby — acetaminophen may be needed to bring your fever down. Provided it’s advised by your doctor, the benefits of acetaminophen use in this case outweigh the potential risks.