Dosing & UsesAdultPediatric Show
Not indicated Dosage Forms & Strengthsmiconazole/petrolatum/zinc oxide topical ointment
Diaper DermatitisIndicated as adjunctive treatment of diaper dermatitis only when complicated by documented candidiasis <4 weeks: Safety and efficacy not established ≥4 weeks: Apply thin layer to diaper area at each diaper change for 7 days AdministrationBefore applying, gently cleanse the skin with lukewarm water and pat dry with a soft towel Avoid using any scented soaps, shampoos, or lotions on the diaper area Continue treatment for the full 7 days, even if there is improvement; do not apply longer than 7 days, if symptoms have not improved by day 7, contact healthcare provider Gently apply a thin layer of ointment to the diaper area with the fingertips; do not rub into the skin as this may cause additional irritation Thoroughly wash hands after application Adverse EffectsPostmarketing ReportsSkin: Burning sensation, condition aggravated, inflammation, pruritus, rash, skin exfoliation WarningsContraindicationsNone CautionsNot a substitute for frequent diaper changes If irritation occurs or worsens, discontinue use and contact healthcare provider Safety and efficacy not demonstrated in immunocompromised patients or incontinent adults Should not be used to prevent diaper dermatitis (ie, adult institutional setting); preventive use may result in drug resistance Pregnancy & LactationPregnancyThere are no available data on ointment use in pregnant women to inform a drug-associated risk for adverse developmental outcomes Animal data
LactationThere is no available information on presence of miconazole in human milk, or effects on breastfed child, or on milk production Consider developmental and health benefits of breastfeeding along with mother’s clinical need for therapy and any potential adverse effects on breastfed infant from drug or from underlying maternal condition Pregnancy CategoriesA: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk. B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done. D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk. X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist. NA: Information not available. PharmacologyMechanism of ActionMiconazole: Antifungal agent; elicits in vitro activity against Candida albicans by inhibiting ergosterol biosynthesis in the cell membrane; accumulation of ergosterol precursors and toxic peroxides results in cytolysis of the cell AbsorptionNegligible Images
Copyright © 2010 First DataBank, Inc. Patient HandoutA Patient Handout is not currently available for this monograph. FormularyFormularyPatient Discounts Adding plans allows you to compare formulary status to other drugs in the same class.
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The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information. View explanations for tiers and restrictions
Non-Medicare Plans Medicare Plans From: To: The recipient will receive more details and instructions to access this offer. By clicking send, you acknowledge that you have permission to email the recipient with this information. From: To: The recipient will receive more details and instructions to access this offer. By clicking send, you acknowledge that you have permission to email the recipient with this information. Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. What is miconazole and zinc oxide topical?What is miconazole and zinc oxide topical? Miconazole and zinc oxide topical (for the skin) is a combination antifungal medicine that fights infections caused by fungus. The ointment form is used to treat diaper rash with yeast infection (candidiasis) in children and babies who are at least 4 weeks old.
Can you mix miconazole and zinc oxide?Miconazole, zinc oxide, and white petrolatum combination is used to treat diaper rash (dermatitis) in infants 4 weeks of age and older with a normal immune system who also have a yeast infection (candidiasis).
Is miconazole nitrate available overMiconazole (Monistat) is available over-the-counter, but is usually more expensive than fluconazole and can cause or worsen things like burning, itching, and irritation.
Can zinc oxide treat fungal infection?Zinc oxide topical will not treat a bacterial or fungal infection. Call your doctor if you have any signs of infection such as redness and warmth or oozing skin lesions.
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Miconazole and zinc oxide topical over the counter
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