I have been diagnosed with spondyloarthritis for several years. I know the disease is separate from rheumatoid, but I’ve been told they are related. What are the similarities / differences in the progression and symptoms and should they be treated the same? RA and spondyloarthritis are quite distinct. RA tends to affect the
peripheral joints (small joints of the hands and feet) and dose not affect the spine. Spondyloarthritis tends to affect the spine with little or no effect on the peripheral joints. The pathogeneic basis for the disease, and associated genetic and autoantibody features are also different. Despite the differences, many of the same medications are used to treat both disorders. There is much more information on these subjects on the Johns Hopkins Arthritis Center Website.  Founded in 1998, the Arthritis Center at Johns Hopkins is dedicated to providing quality education to patients and healthcare providers alike. Rheumatic Arthritis vs Ankylosing Spondylitis How a number of diseases start or come about still remains a big mystery for doctors who try to explain these phenomena. In certain circumstances, some of the disease’s etiology or origin becomes unknown. For the medically inclined, the unknown origin of a disease is termed as “idiopathic.” Additionally, these types of diseases are said to be caused by the body’s own defenses, the immune system. Instead of fighting off foreign bodies and harmful microorganisms who try to invade the body, the body’s own immune system combats the body system itself. Due to unknown reasons, the body is compromised from undue attacks from the immune responses created. These diseases that are caused by the body’s own immune system response are called autoimmune diseases. A very commonly heard condition that affects a rapidly increasing number of individuals nowadays is what we call as rheumatic arthritis or simply termed as RA. Rheumatic arthritis is an autoimmune disorder of the musculoskeletal system wherein it affects bones, joints, and even organs. It is mainly characterized by an inflammation and stiffening of the joints mostly located in the extremities in both the hands and feet. It is distinguished by its bilateral involvement of both joints. RA is one of the autoimmune disorders that cause a great deal of pain for the affected individual. However, quite a few other types of rheumatic diseases are much alike in characteristics to RA. One of its closely similar disease relations is what is called ankylosing spondylitis. Though both conditions fall under the autoimmune class of diseases, a number of differences are then spotted to distinguish between the two. Ankylosing spondylitis, like RA, is an autoimmune disorder that affects the bones, joints, and organs. Yet, unlike RA, it does not mainly involve the joints of the extremities but instead is characterized by affecting the mobility of the spine and sacroiliac joints. Ankylosing spondylitis (AS) is a progressive inflammation and stiffening of the spine and its parts. In the long run, AS may lead to vertebral fusing and eventually may cause a bent posture. In terms of affected bony parts, AS mostly affects the axial skeleton while it rarely does for RA. Anatomically speaking, RA usually causes a great deal of inflammation in the synovium or the membrane that serves as a lining around the joints. On the other hand, AS causes inflammation to the enthesis, the location where the bone is inserted by a tendon. Both diseases are characterized by remissions and exacerbations. Rheumatoid arthritis and ankylosing spondylitis manifest a group of similar symptoms. Both disorders involve experiencing morning stiffness, nausea, malaise, and fatigue. Though they have the same set of symptoms, RA commonly occurs in females triple in number while AS is more frequent by a third for the male group. Both diseases appear at the start of the individual’s adult life. AS starts a little earlier with its peak onset between the ages of 20 to 30 years old while RA peaks a little later in the adult life between the ages of 30 to 40 years old. Due to heart disease complications, RA appears to have a greater influence on mortality for the affected individuals unlike AS. On the bottom line, like any other autoimmune or rheumatic diseases, rheumatoid arthritis and ankylosing spondylitis are both indiscernible conditions that have affected lives disruptively. Because of chronic pain and eventual disability, the track of an affected individual’s life is completely changed. It is therefore imperative that supportive management is necessary to alleviate the suffering from these mysterious conditions. Summary: 1.RA mainly involves the joints of the extremities while AS is characterized by affecting the mobility of the spine and sacroiliac joints. 2.In terms of affected bony parts, AS mostly affects the axial skeleton while it rarely does for RA. 3.RA usually causes a great deal of inflammation in the synovium or the membrane that serves as a lining around the joints. On the other hand, AS causes inflammation to the enthesis, the location where the bone is inserted by a tendon. 4.RA commonly occurs in females triple in number while AS is more frequent by a third for the male group. 5.AS starts a little earlier with its peak onset between the ages of 20 to 30 years old while RA peaks a little later in the adult life between the ages of 30 to 40 years old. 6.Due to heart disease complications, RA appears to have a greater influence on mortality for the affected individuals unlike AS.
Loading... Cite Can you have both rheumatoid arthritis and ankylosing spondylitis?Today there are no major diagnostic difficulties in differentiation between these diseases, thanks to modern laboratory tests and imaging. However, a problem may arise when the patient has symptoms typical for both diseases simultaneously. Cases of coexistence of RA with AS – according to our best knowledge – are rare.
What is the difference between rheumatoid arthritis and spondyloarthritis?RA tends to affect the peripheral joints (small joints of the hands and feet) and dose not affect the spine. Spondyloarthritis tends to affect the spine with little or no effect on the peripheral joints. The pathogeneic basis for the disease, and associated genetic and autoantibody features are also different.
How can you tell the difference between ankylosing spondylitis and reactive arthritis?Overview of Reactive Arthritis. Reactive arthritis (ReA) is a form of arthritis that can cause inflammation and pain in the joints, skin, eyes, bladder, genitals, and mucus membranes. Unlike ankylosing spondylitis, ReA does not normally affect the spine and the sacroiliac joints in a majority of cases.
What type of arthritis is ankylosing spondylitis?Ankylosing spondylitis (AS) is a type of inflammatory arthritis that affects the spine and the sacroiliac joints that attach the pelvis to the base of the spine. 'Ankylosing' means fusing and 'spondylitis' means inflammation of the spine.
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Difference between ankylosing spondylitis and rheumatoid arthritis
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